Organization Of The Body Assignment Answer

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Task 1 A:

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5. Put the following body systems in order from left to right

Answer:

Nervous system

Respiratory system

Cardiovascular system

Digestive system

Musculoskeletal system

Skeletal system

6. Put the Following in correct order of size from smallest to largest

Answer

Cell

Tissue

Organ

Organ system

7. Identify the following organs in order from the respiratory system diagram below – 4,8,10 and 11

Answer: Right Lung, Trachea, Bronchiole and Alveoli

8. What is the function of the Trachea?

Answer: A passageway through which the air passes from the upper respiratory tract to the bronchi.

9. What is the function of the Alveoli?

Answer: To assist in the exchange of oxygen and carbon dioxide between the blood and lungs.

10. Identify the following organs in order from the human cardiovascular system diagram below -2, 4, 5 and 10.

Answer: Right Ventricle, Capillaries, Pulmonary vein and Vana Cava

11. What is the function of the left ventricle?

Answer: Responsible for pumping blood into the aorta and to tissues all around the body.

12. What is the function of the vena cava?

Answer: Transports deoxygenated blood to the right atrium of the heart.

13. Identify the following organs in order from the digestive system diagram below – 2, 4, 6 and 10.

Answer: Oesophagus, Small intestine, Anus and Liver

14. What is the function of the stomach?

Answer: The storage and breakdown of food/chyme through churning and the production of hydrochloric acid.

15. What is the function of the pancreas?

Answer: Production of pancreatic juices which contain enzymes that aid in digestion, and it produces several hormones, including insulin.

Task 1 B:

The exchange of oxygen and carbon dioxide is the main task of the respiratory system (Wheeldon, 2023). Through inhalation, oxygen is taken in and circulated through the circulatory system to the body's tissues. During exhalation, it simultaneously gets rid of carbon dioxide, a metabolic waste product.

The cardiovascular system, which is made up of the heart and blood arteries, conveys blood that is rich in oxygen from the lungs to the body's cells and returns blood that is heavy in carbon dioxide to the lungs for exhalation (Saghiv et al. 2020). This system guarantees that waste products are removed and that oxygen reaches the cells where energy is produced.

Contrarily, the digestive system is in charge of turning food into nutrients that are absorbed into the bloodstream. Then, for energy, growth, and repair, the circulatory system transfers these nutrients to cells.

These systems work together to sustain living by assuring a constant flow of oxygen, nutrients, and waste elimination. They work in unison to keep the body healthy and functioning effectively, with the cardiovascular system serving as the network of pathways that connect the respiratory and digestive systems (Elbers, 2020). The life and general health of the organism depend on this concerted effort.

Task 2:

(A) The three cubes stand for various sizes and surface area to volume ratios. The surface area-to-volume ratio drops as the cubes get bigger. For effective nutrition exchange, waste elimination, and temperature regulation in big organisms, a high surface area to volume ratio must be maintained. Smaller cells can swiftly exchange materials with their environment because they have a bigger surface area compared to volume than larger cells. Larger cells would have difficulty efficiently transporting necessary molecules and getting rid of waste because of their lower surface area to volume ratio (Roy et al. 2021).

Vast organisms are able to maximise these crucial activities because they have a vast number of microscopic cells, ensuring that each cell can easily acquire nutrients and oxygen as well as efficiently eliminate waste. The survival and development of large and sophisticated organisms are supported by this network of numerous, smaller cells that enable essential functions (Newman, 2023).

(B) Organisms need specialised cells and tissues to thrive since they must carry out a variety of bodily activities as well as deal with a variety of environmental obstacles. By improving efficiency and adapting to certain tasks, specialisation maximises an organism's chances of surviving (von Schmalensee et al. 2023). Specialised tissues and cells carry out a variety of tasks. For example, muscle cells are designed for contraction and movement, whereas nerve cells are customised for the transmission of electrical signals. The body's surfaces are covered and protected by tissues, including epithelial tissue. Utilising resources effectively is another benefit of specialisation. Red blood cells, for example, are specially designed to transport oxygen thanks to their biconcave structure and haemoglobin (Chen et al. 2023).

TASK 3: Cells everywhere!

Answer:

Egg Cell - Sperm cells are designed specifically to fertilise eggs. They move towards the egg using a long, whip-like tail structure called a flagellum (Rahban, 2020). DNA that is packed closely within the head is genetic material that is necessary for fertilisation. The acrosome, a cap-like structure at the head, has enzymes that help the sperm reach the egg by dissolving its defences. The successful union of genetic material during fertilisation is ensured by the streamlined structure's mobility and penetration.

Egg cell

Figure 1: Egg cell

Ovum (Egg cell) - The female reproductive cells called ova are created for fertilisation. They are nutrient-rich, spherical, and reasonably sized to feed the growing embryo (Cao et al. 2022). Half of the genetic material needed for the offspring is present in the ovum. The zona pellucida, which is its protective outer layer, is crucial for sperm identification and union. It is the perfect choice for sustaining early embryonic development due to its size and nutrient content.

Ovum cell

Figure 2: Ovum cell

Neuron (Nerve Cell) - Neurons selectively send electrical signals. They have a long axon that can carry electrical impulses over considerable distances (Drukarch, 2023). Dendrites receive impulses from other neurons. At synapses the connections between neurotransmitters assist in the signal transmission process. Neurons have myelin sheaths, which shield and speed up signal transmission along the axon. Neurons must have a specific shape and structure in order to contribute to the rapid and efficient communication that occurs throughout the nervous system.

Neuron cell

Figure 3: Neuron cell

(Source: msdmanuals.com, 2023)

Ileum's Epithelial Cells - The ileum's epithelial cells are trained specifically for the small intestine's nutrient absorption (Kelly et al. 2022). They have small finger-like projections called microvilli that increase the surface area available for absorption. These cells also include transport proteins that help nutrients traverse the cell membrane more easily. This specialisation facilitates effective nutrition absorption and supports the small intestine's absorptive and digesting processes.

Ileum's Epithelial Cells

Figure 4: Ileum's Epithelial Cells

Task 4: Everything in the human body is made of only FOUR BASIC kinds of tissue: nervous, muscular, epithelial, and connective tissue. Research and answer the following questions

Tissue Type

Features of Tissue

Two Areas Found in the Body

Function of Tissue in that Part of the Body

A: Epithelial

Sheets of closely packed cells

Apical surface (free surface)

1. Skin (Epidermis)

2. 2. Lining of digestive tract (intestinal epithelium)

1. Protection, barrier against pathogens and environmental factors.

2. Absorption, secretion, and selective permeability.

B: Muscular

Elongated cells capable of contraction

Striated appearance (in skeletal and cardiac muscles)

1. Skeletal muscles

2. 2. Heart (cardiac muscle)

1. Voluntary movement and locomotion.

2. 2. Pumping blood through the circulatory system (cardiac) and various body movements (skeletal).

C: Connective

Diverse cell types (e.g., fibroblasts, adipocytes)

Extracellular matrix (e.g., collagen fibers)

1. Bone (Osseous tissue)

2. 2. Blood (as plasma)

1. Support, protection, and mineral storage.

2. 2. Transport of oxygen, nutrients, and waste products.

D: Nervous

Neurons (nerve cells) for signal transmission

Glial cells for support and protection

1. Brain (neural tissue)

2. Spinal cord (nerve tissue)

1. Processing and integration of information, control of body functions.

2. Conduction of electrical signals and coordination of responses.

Epithelial tissue - Sheets of densely packed cells make up the epithelial tissue that covers different bodily surfaces (Teng, 2021). It creates the skin's epidermis and provides defence against diseases and the elements. It lines the internal surface of the digestive tract, promoting absorption, secretion, and selective permeability. Epithelial cells frequently specialise their apical surface (free surface) to match their tasks.

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Muscular Tissue - Long, contractile cells make the elongated structure of muscle tissue. Skeletal muscles are those that are located in muscles connected to bones and facilitate locomotion and voluntary movement (Banerjee, 2023). Smooth muscles control numerous internal organ activities, while cardiac muscles in the heart pump blood through the circulatory system. Striated appearance results from the alignment of contractile units, especially in skeletal and cardiac muscles.

Connective Tissue - Diverse cell types, including adipocytes and fibroblasts, are found in connective tissue (Aprile et al. 2021). These cells are embedded in an extracellular matrix made up of proteins like collagen. Support, defence, and mineral storage are all provided by it in osseous tissue, which includes bone tissue. In its plasma form, blood, a sort of connective tissue, transports nutrients, waste materials, and oxygen throughout the body.

Nervous Tissue - Neurons (nerve cells), which convey electrical signals, and glial cells, which provide support and protection, make up nervous tissue (Halim et al. 2021). It is mostly located in the brain and spinal cord, where it integrates and processes information to regulate different bodily activities (Patton et al. 2023). Axons, dendrites, and the cell body of neurons all play distinct roles in the coordination of actions and the transmission of signals.

Task 5: Stem cells: grow your own organs

Due to their exceptional qualities, which make them a plausible alternative for replacing damaged cells, particularly in regions with restricted regenerative capacity like the brain, stem cells have become a hot topic in the last two decades. We must delve into the crucial characteristics that differentiate stem cells from specialised cells in order to fully grasp their potential. The ability of stem cells to develop into distinct cell types is known as their potency (Tomokiyo, Wada and Maeda, 2019). Totipotent stem cells have the extraordinary ability to develop into any type of human cell, including extraembryonic and embryonic cells. One illustration is the zygote, which is created when an egg and sperm combine and can grow into a full organism.

All three germ layers can be formed from pluripotent stem cells, but they cannot develop into extraembryonic tissues. An illustration would be embryonic stem cells (ESCs), which can differentiate into a variety of cell types but not extraembryonic structures (Poliwoda et al. 2022). Although more limited in their ability to differentiate, multipotent stem cells can nevertheless produce a variety of specialised cells. For instance, hematopoietic stem cells in the bone marrow can produce blood cells including red blood cells, white blood cells, and platelets. In contrast, specialised cells, such as neurons, cardiac muscle cells, or hepatocytes, are terminally differentiated and carry out particular tasks inside tissues or organs. Unlike stem cells, which still have this capacity for regeneration, they are no longer able to develop into other types of cells.

There are multiple steps in the stem cell-based tissue engineering process:

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Cell acquisition: A variety of sources can be used to obtain stem cells. While induced pluripotent stem cells (iPSCs) are reprogrammed from adult cells, embryonic stem cells are produced from embryos (Ray et al. 2021). In tissues like bone marrow, adipose tissue, or cord blood, adult stem cells can be detected. Through biopsy or other minimally invasive methods, these cells are carefully collected.

Cell Nurturing: After being acquired, stem cells are cultivated and raised in a sterile setting. In order to maintain the right conditions for the cells to multiply and differentiate as required, nurturing is necessary. To direct the cells towards the chosen differentiation path, growth factors, hormones, and certain culture media are utilised (O'Neill et al. 2021).

Directed Differentiation: Stem cells are stimulated to become the particular cell types needed for the target tissue or organ (Fu et al. 2019). By adjusting growth factors, signalling molecules, and environmental cues, stem cells can be guided along the correct developmental pathways.

Formation of Tissues or Organs: Differentiated stem cells are then put together to form tissues or organs that function. Differentiated neuronal cells in neural tissue, for instance, may be arranged into a 3D pattern that resembles the organisation of the brain. Complex structures can be made using a variety of methods, such as tissue engineering and 3D bioprinting (Feng et al. 2021).

In conclusion, stem cells present a promising way to replace missing or injured body parts, especially in regions like the brain where neuron regeneration is constrained. Obtaining the right stem cell source, fostering and directing their development, and finally producing functioning tissues or organs for therapeutic uses are the stages of tissue engineering. While stem cell research is still developing, it has the potential to completely change regenerative medicine and enhance the lives of people with a variety of degenerative diseases.

References

  • Aprile, D., Alessio, N., Demirsoy, I.H., Squillaro, T., Peluso, G., Di Bernardo, G. and Galderisi, U., 2021. MUSE stem cells can be isolated from stromal compartment of mouse bone marrow, adipose tissue, and ear connective tissue: a comparative study of their in vitro properties. Cells, 10(4), p.761.
  • Banerjee, D. and Das, P.K., 2023. Check for updates Muscular System Dipak Banerjee, Pradip Kumar Das, and Joydip Mukherjee. Textbook of Veterinary Physiology, p.235.
  • Cao, M., Schwartz, H.T., Tan, C.H. and Sternberg, P.W., 2022. The entomopathogenic nematode Steinernema hermaphroditum is a self-fertilizing hermaphrodite and a genetically tractable system for the study of parasitic and mutualistic symbiosis. Genetics, 220(1), p.iyab170.
  • Chen, M., Leng, Y., He, C., Li, X., Zhao, L., Qu, Y. and Wu, Y., 2023. Red blood cells: a potential delivery system. Journal of Nanobiotechnology, 21(1), pp.1-19.
  • Drukarch, B. and Wilhelmus, M.M., 2023. Thinking about the action potential: the nerve signal as a window to the physical principles guiding neuronal excitability. Frontiers in cellular neuroscience, 17.
  • Elbers, J. and McCraty, R., 2020. HeartMath approach to self-regulation and psychosocial well-being. Journal of Psychology in Africa, 30(1), pp.69-79.
  • Feng, Y., Zhu, S., Mei, D., Li, J., Zhang, J., Yang, S. and Guan, S., 2021. Application of 3D printing technology in bone tissue engineering: a review. Current Drug Delivery, 18(7), pp.847-861.
  • Fu, X., Liu, G., Halim, A., Ju, Y., Luo, Q. and Song, G., 2019. Mesenchymal stem cell migration and tissue repair. Cells, 8(8), p.784.
  • Halim, A., Qu, K.Y., Zhang, X.F. and Huang, N.P., 2021. Recent advances in the application of two-dimensional nanomaterials for neural tissue engineering and regeneration. ACS Biomaterials Science & Engineering, 7(8), pp.3503-3529.
  • Kelly, J., Al-Rammahi, M., Daly, K., Flanagan, P.K., Urs, A., Cohen, M.C., di Stefano, G., Bijvelds, M.J., Sheppard, D.N., de Jonge, H.R. and Seidler, U.E., 2022. Alterations of mucosa-attached microbiome and epithelial cell numbers in the cystic fibrosis small intestine with implications for intestinal disease. Scientific Reports, 12(1), p.6593.
  • Newman, S.A., 2023. Inherency and agency in the origin and evolution of biological functions. Biological Journal of the Linnean Society, 139(4), pp.487-502.
  • O'Neill, E.N., Cosenza, Z.A., Baar, K. and Block, D.E., 2021. Considerations for the development of cost?effective cell culture media for cultivated meat production. Comprehensive Reviews in Food Science and Food Safety, 20(1), pp.686-709.
  • Patton, K.T., Bell, F.B., Thompson, T., Williamson, P.L. and Sun, E.L., 2023. Study Guide for The Human Body in Health & Disease-E-Book.
  • Poliwoda, S., Noor, N., Downs, E., Schaaf, A., Cantwell, A., Ganti, L., Kaye, A.D., Mosel, L.I., Carroll, C.B., Viswanath, O. and Urits, I., 2022. Stem cells: a comprehensive review of origins and emerging clinical roles in medical practice. Orthopedic Reviews, 14(3).
  • Rahban, R. and Nef, S., 2020. CatSper: The complex main gate of calcium entry in mammalian spermatozoa. Molecular and cellular endocrinology, 518, p.110951.
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  • Tomokiyo, A., Wada, N. and Maeda, H., 2019. Periodontal ligament stem cells: regenerative potency in periodontium. Stem cells and development, 28(15), pp.974-985.
  • von Schmalensee, L., Caillault, P., Gunnarsdóttir, K.H., Gotthard, K. and Lehmann, P., 2023. Seasonal specialization drives divergent population dynamics in two closely related butterflies. Nature Communications, 14(1), p.3663.
  • Wheeldon, A., 2023. The respiratory system and associated disorders. British Journal of Nursing, 32(13), pp.613-619.
  • Websites:
  • altrui.co.uk, 2023, Human egg cells, Available at: https://www.altrui.co.uk/resources/the-human-egg-cell-explained/ [Accessed on: 11th October 2023]
  • stock.adobe.com, 2023, Ovum egg cells, Available at: https://stock.adobe.com/in/images/female-egg-cell-with-cytoplasm-nucleus-plasma-membrane-ovum-reproductive-cell-gamete-structure-vector-illustration-isolated-on-white-background-for-education-schools-univercity-and-clinics/365774040 [Accessed on: 11th October 2023]
  • msdmanuals.com, 2023, Neuron cell, Available at: https://www.msdmanuals.com/home/multimedia/figure/typical-structure-of-a-nerve-cell [Accessed on: 11th October 2023]
  • nature.com, 2023, Ileum's Epithelial Cells, Available at: https://www.nature.com/articles/nri3608 [Accessed on: 11th October 2023]

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